Developing blah blah blah
Poop Pills
A scientific methodology
Solution
Impact
Design a way to deliver poop in pill form.

Over 250k pills have been made using my method. To date, the pill I designed has treated over 2,000 patients with C. diff and has been used to study the effects of FMT in 25+ clinical trials including inflammatory bowel disease (IBD), immunoncology (I/O), and primary sclerosing cholangitis (PSC).

I increased access to Fecal Transplants by developing and launching a poop pill to treat patients with C. diff infection

Background
Clostridium difficile, also known as “C. diff,” inflicts debilitating symptoms, kills almost 30,000 of the 500,000+ Americans it affects each year.

When antibiotics don’t work on this common hospital infection, a Fecal Microbiota Transplant (FMT) can be used to send an army of good bacteria into your gut to crowd out the infection. Patients feel better within hours 90 percent of the time! FMT works in just the opposite way antibiotics do. Where antibiotics wipe out infection, FMT overflows the area, leaving the infectious bacteria with nowhere to hide. Until 2015, doctors would administer an FMT via a colonoscopy or endoscopy tube, an invasive but effective medical procedure.

Problem Space
Design a way to deliver poop in pill form.

Fecal matter is not the easiest thing to encapsulate. It’s 70 percent water; when you put it into a gelatin capsule, a traditional shell for drugs, the capsule melts from the inside out.

Say hello to MEM Tech!

After the initial design and development, I worked with manufacturing technicians to scale and standardize the operating procedures.

I created MEM Tech (Microbial Emulsion Matrix Technology), which is an emulsion where a hydrophobic (water-hating) liquid acts as a small "fence" around the hydrophilic (water-loving) bubbles of poop.

Process

From prototypes to poop geysers, have a peek into my process.

When

Sept 2014 - July 2015

Company

OpenBiome, non profit biotechnolgy startup

In the News

OpenBiome, non profit biotechnolgy startup